Fructose-based Softdrinks Blamed for Gout Incidence

Sunday, January 11, 2009

The annual meeting of the British Society for Rheumatology recently disclosed the findings of their study about the sharp increase in gout among American adults that has occurred in recent decades was partly because of their consumption of soft drinks containing fructose.
Since the advent of the use of high-fructose corn-syrup in the sweetening of soft drinks there has been an increase in its consumption. It is found out that since the steady increase in its consumption there has been a steady increase in of gout incidence among adults who consumed these soft drinks.
Lay persons who have been afflicted of gout and those of us who have a medical background know that the conventional "low purine" diet is the widely accepted regimen for gout stricken individuals because uric acid is the breakdown product of purine. However, a rheumatologist at the University of British Columbia, Vancouver found out that fructose can increase uric acid production by breaking down adenosine triphosphate into adenosine monophosphate, a uric precursor.
Fructose also contributes to impaired glucose tolerance and increase insulin resistance and hyperinsulinemia which could indirectly elevate serum uric acid levels.
Studies have found out in adults who consumed about 5-6 servings of sugary soft drinks per week had a multivariate relative risk of 1.29, there has been also an 85% increase in gout incidence among those who consumed two or more soft drinks per day.
Another study found out that drinking coffee may be protective, but only if it is drunk in considerable quantities. They have found out that serum uric acid levels in individuals drinking six cups of coffee per day were significantly lower by 0.43 mg/dL than those who did not drink coffee. They think that the chlorogenic acid in coffee is responsible, which is a powerful anti-oxidant.
In conclusion, people should halt dietary intake of sugary soft drinks if not limit it into moderation, not only for gout prevention but also for the common comorbidities it can cause and coffee intake is also beneficial.

*Taken from an article in the Philippine Star dated January 11, 2009.


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